Description

Phosphatidylethanolamines, Escherichia Coli is a high-purity phospholipid derived from the *E. coli* bacterial membrane, with the CAS registry number 94581-14-3. This natural-source lipid is a critical component for constructing biomimetic membranes and vesicles, offering superior consistency and biological relevance compared to synthetic alternatives. It is essential for researchers and manufacturers in the life sciences, particularly for developing advanced drug delivery systems, membrane protein studies, and diagnostic reagents.

Application

• Liposome & Nanoparticle Formulation: A key structural phospholipid for creating stable, biocompatible liposomes used in targeted drug delivery and mRNA vaccine formulations.
• Membrane Biology Research: Used to create model cell membranes (e.g., supported lipid bilayers, giant unilamellar vesicles) for studying membrane protein function, fusion processes, and cellular signaling.
• Cell Culture & Media Supplements: Employed as a raw material in specialized serum-free media and supplements to support the growth of sensitive cell lines.
• Diagnostic Reagent Production: Serves as a component in diagnostic kits, such as those for autoimmune disease detection, where specific membrane antigens are presented.
• Biophysical Studies: Utilized in calorimetry, spectroscopy, and microscopy to investigate lipid-lipid and lipid-protein interactions.
• Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products for its skin-barrier repair and moisturizing properties.

Basic Information

Product Name	Phosphatidylethanolamines, Escherichia Coli
CAS No.	94581-14-3
Molecular Formula	Typically C41H78NO8P (for a major species, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine)
Molecular Weight	~744.0 g/mol (varies by fatty acid composition)
Synonyms	E. coli PE; 1,2-Diacyl-sn-glycero-3-phosphoethanolamine; Phosphatidylethanolamine (E. coli); PE (E. coli); 3-sn-Phosphatidylethanolamine; 1,2-Diacylglycerophosphoethanolamine; Bacterial Phosphatidylethanolamine; PtdEtn
EINECS	Contact for details

Quality Control

Our Phosphatidylethanolamines, Escherichia Coli is produced under stringent conditions to ensure batch-to-batch reproducibility and high purity, suitable for research and GMP-grade applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, fatty acid profile, and oxidation status. We adhere to rigorous internal quality standards and can provide material traceability documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Once opened, use promptly and purge the container with inert gas before resealing.

Specification

Item	Specification
Appearance	White to light yellow powder or waxy solid
Identification (TLC/IR)	Conforms to standard
Assay (HPLC)	≥ 98% (Total Phosphatidylethanolamine)
Phospholipid Profile	≥ 99% (PE content of total phospholipids)
Peroxide Value (PV)	< 2.0 meq/kg
Lyso-Phosphatidylethanolamine	< 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.