Description

2,5-Bis(4-Hydroxyphenyl)Piperazine Dihydrochloride is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of complex pharmaceutical intermediates and specialty polymers. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate its unique di-phenolic and di-amine functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the production of high-performance, heat-resistant epoxy resins and polyimides.
• Ligand Synthesis: Used in the preparation of chelating ligands for catalysis and metal ion complexation studies.
• Agrochemical Research: Employed as a building block for developing new active ingredients with specific biological activity.
• Material Science: Investigated for creating advanced organic frameworks and functional materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	2,5-Bis(4-Hydroxyphenyl)Piperazine Dihydrochloride
CAS No.	94572-68-6
Molecular Formula	C16H20Cl2N2O2
Molecular Weight	343.25 g/mol
Synonyms	2,5-Bis(4-hydroxyphenyl)piperazine dihydrochloride; 1,4-Bis(4-hydroxyphenyl)-2,5-piperazinedione dihydrochloride (common misnomer); 2,5-Di(4-hydroxyphenyl)piperazine dihydrochloride; BHP Dihydrochloride; 2,5-Bis(p-hydroxyphenyl)piperazine dihydrochloride; Piperazine, 2,5-bis(4-hydroxyphenyl)-, dihydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,5-Bis(4-Hydroxyphenyl)Piperazine Dihydrochloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.