Description

(25R)-15α-[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyloxy]-26-Acetoxycholest-5-En-3β-Ol is a high-purity, semi-synthetic steroidal glycoside of significant interest in advanced pharmaceutical research and development. This compound matters as a key intermediate or reference standard for the synthesis and study of novel bioactive molecules, particularly in the fields of endocrinology and oncology. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of steroid-based therapeutics, diagnostic agents, and high-value biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating steroid receptor interactions, metabolic pathways, and cellular signaling mechanisms.
• API Development: Acts as a precursor in the research and development of new Active Pharmaceutical Ingredients (APIs) with targeted therapeutic effects.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for clinical diagnostics and laboratory testing kits.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and pharmacology.
• Process Development & Scale-up: Supports process optimization and scale-up activities from laboratory to pilot plant scale for commercial manufacturing.

Basic Information

Product Name	(25R)-15α-[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyloxy]-26-Acetoxycholest-5-En-3β-Ol
CAS No.	94480-49-6
Molecular Formula	C₃₈H₆₃NO₉
Molecular Weight	677.91 g/mol
Synonyms	15α-(2-Acetamido-2-deoxy-β-D-glucopyranosyloxy)-26-acetoxycholest-5-en-3β-ol; (25R)-26-Acetoxy-15α-[(2-acetylamino-2-deoxy-β-D-glucopyranosyl)oxy]cholest-5-en-3β-ol; 15α-GlcNAc-26-acetoxy-cholesterol; Steroidal N-acetylglucosaminide; 15-Deoxy-15α-(2-acetamido-2-deoxy-β-D-glucopyranosyloxy)-26-acetoxycholest-5-en-3β-ol
EINECS	Contact for details

Quality Control

Our (25R)-15α-[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyloxy]-26-Acetoxycholest-5-En-3β-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.