Description

(2Ar,6Bβ,7Aβ,7Bα,8R)-Octahydro-2Aα,6Aα-Dihydroxy-7Cα-Methyl-8-(1-Methylethenyl)-3α,6α-Methano-2,4,7-Trioxacyclopenta[Cd]Cycloprop[A]Azulen-5(6H)-One is a complex sesquiterpene lactone derivative, a high-value synthetic intermediate prized for its intricate polycyclic framework. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive molecules. It is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential drug candidates, especially in anti-inflammatory and anticancer research.
• Advanced Organic Synthesis: Used in complex total synthesis projects to construct challenging polycyclic and bridged ring systems.
• Medicinal Chemistry Research: Acts as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Investigated as a precursor for novel bioactive compounds with potential pesticidal or herbicidal activity.
• Chemical Biology Probe: Utilized in research to study biological pathways and protein interactions due to its unique three-dimensional structure.
• Academic & Institutional R&D: A valuable compound for universities and research institutes focusing on synthetic methodology and natural product analogs.

Basic Information

Product Name	(2Ar,6Bβ,7Aβ,7Bα,8R)-Octahydro-2Aα,6Aα-Dihydroxy-7Cα-Methyl-8-(1-Methylethenyl)-3α,6α-Methano-2,4,7-Trioxacyclopenta[Cd]Cycloprop[A]Azulen-5(6H)-One
CAS No.	94451-13-5
Molecular Formula	C15H18O6
Molecular Weight	294.30 g/mol
Synonyms	8-Isopropenyl-2,6-dihydroxy-7-methyl-3,6-methano-2,4,7-trioxacyclopenta[cd]cyclopropa[a]azulen-5(6H)-one; Parthenolide analog; Parthenolide derivative; Sesquiterpene lactone intermediate; 3,6-Methano-2,4,7-trioxacyclopenta[cd]cyclopropa[a]azulen-5(6H)-one derivative; Octahydro-2α,6α-dihydroxy-7α-methyl-8-(1-methylethenyl)-3α,6α-methano-2,4,7-trioxacyclopenta[cd]cyclopropa[a]azulen-5-one
EINECS	Contact for details

Quality Control

Our (2Ar,6Bβ,7Aβ,7Bα,8R)-Octahydro-2Aα,6Aα-Dihydroxy-7Cα-Methyl-8-(1-Methylethenyl)-3α,6α-Methano-2,4,7-Trioxacyclopenta[Cd]Cycloprop[A]Azulen-5(6H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.