Description

C22 Sphingomyelin (D18:1/22:0) is a high-purity, defined sphingolipid essential for advanced life science research and pharmaceutical development. This specific molecular species is critical for studying membrane structure, lipid rafts, and cellular signaling pathways. It is a key material for researchers and formulators in the pharmaceutical, biotechnology, and nutraceutical industries developing lipid-based delivery systems and investigating neurological and metabolic disorders. CAS NO 94359-12-3.

Application

• Biomedical Research: Fundamental studies on cell membrane biophysics, lipid raft formation, and apoptosis signaling.
• Drug Delivery Systems: A critical component in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted therapeutic delivery.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control of complex lipid products.
• Neuroscience Research: Investigation of myelin sheath composition and function, and its role in neurodegenerative diseases.
• Cosmetic Science: Incorporation into high-end skincare formulations for its role in skin barrier function and ceramide precursor activity.
• Diagnostic Reagent Development: Used in the production of assay kits and calibrators for clinical lipidomics.

Basic Information

Product Name	C22 Sphingomyelin (D18:1/22:0)
CAS No.	94359-12-3
Molecular Formula	C45H91N2O6P
Molecular Weight	787.19 g/mol
Synonyms	N-(22:0)-D-erythro-Sphingosylphosphorylcholine; N-Docosanoyl-D-erythro-sphingosylphosphorylcholine; SM(d18:1/22:0); (2S,3R,4E)-2-[(Docosanoylamino]-4-octadecene-1,3-diol 1-(Dihydrogen phosphate) 2-(Trimethylammonio)ethyl ester; Sphingomyelin (18:1/22:0); Sphingomyelin (d18:1/22:0); N-Docosanoylsphingomyelin
EINECS	Contact for details

Quality Control

Our C22 Sphingomyelin (D18:1/22:0) is manufactured under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.