Description

α-2,4-Trimethyl-1,3-Dioxolane-2-Methanol is a specialized organic compound belonging to the dioxolane family, valued for its unique structure as a protected diol or masked aldehyde precursor. Its primary commercial value lies in its utility as a versatile chiral building block and protecting group reagent in sophisticated organic synthesis. This chemical is particularly essential for research and production in the pharmaceutical and fine chemical industries, where it facilitates the creation of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material for constructing enantiomerically pure compounds in academic and industrial research.
• Protecting Group Chemistry: Used to protect sensitive aldehyde or diol functionalities during multi-step synthetic sequences, owing to its stability under various conditions.
• Fragrance and Flavor Industry: Acts as a precursor for synthesizing specific aroma chemicals and flavoring agents with desired stereochemistry.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands for asymmetric catalysis and metal-organic frameworks.
• Polymer Science: Can be incorporated as a monomer or cross-linking agent for producing specialty polymers with specific functional properties.

Basic Information

Product Name	α-2,4-Trimethyl-1,3-Dioxolane-2-Methanol
CAS No.	94089-23-3
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	2-(Hydroxymethyl)-2,4,5-trimethyl-1,3-dioxolane; (2,4,5-Trimethyl-1,3-dioxolan-2-yl)methanol; 1,3-Dioxolane-2-methanol, 2,4,5-trimethyl-; Trimethyl dioxolane methanol; Dioxolane methanol derivative; Chiral dioxolane building block; Acetal-protected glycerol derivative
EINECS	Contact for details

Quality Control

Our α-2,4-Trimethyl-1,3-Dioxolane-2-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Specifications are designed to meet the rigorous demands of research and cGMP-guided production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flame. Ensure containers are kept tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Optical Purity (Chiral GC/HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.