Description

(1R,4R)-4-Methylcyclohexanecarbaldehyde is a high-purity chiral aldehyde building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive carbonyl group make it a valuable precursor for creating complex, optically active molecules. This compound is particularly sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, chiral ligand development, and the production of specialty fragrances and flavors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Catalysis: Used in the development and testing of novel chiral catalysts and ligands.
• Fine Chemical Synthesis: Serves as a building block for complex natural products, specialty polymers, and advanced materials.
• Fragrance & Flavor Chemistry: A precursor for creating specific, high-value odorants and flavoring agents with defined sensory profiles.
• Agrochemical Research: Employed in the synthesis of chiral bioactive compounds for crop protection.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(1R,4R)-4-Methylcyclohexanecarbaldehyde
CAS No.	7133-05-3
Molecular Formula	C8H14O
Molecular Weight	126.20 g/mol
Synonyms	(1R,4R)-p-Menthane-8-carboxaldehyde; (1R,4R)-4-Methylcyclohexylcarboxaldehyde; (-)-trans-4-Methylcyclohexanecarboxaldehyde; (R,R)-4-Methylcyclohexanecarbaldehyde; trans-(1R,4R)-4-Methylcyclohexanecarbaldehyde; 4-Methylcyclohexanecarboxaldehyde, (1R,4R)-(-)-; (1R,4R)-(-)-4-Methylcyclohexanecarbaldehyde
EINECS	Contact for details

Quality Control

Our (1R,4R)-4-Methylcyclohexanecarbaldehyde is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, GC for chemical purity, and identity confirmation via FT-IR and NMR. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.