Description

3-Bromo-3,5-Difluoropropanal Diethyl Acetal is a valuable fluorinated building block and protected aldehyde intermediate used in advanced organic synthesis. This compound is critical for the efficient introduction of bromine and fluorine atoms into complex molecular architectures, enabling the development of novel active ingredients. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of fluorinated target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where fluorine substitution enhances biological activity and stability.
• Material Science Research: Serves as a precursor for fluorinated monomers or polymers with specialized properties like chemical resistance or low surface energy.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Protected Aldehyde Synthon: The acetal group protects the aldehyde functionality, allowing for selective reactions at other sites before deprotection.
• Fluorine Chemistry Exploration: An essential reagent for academic and industrial research focused on incorporating difluoromethylene (CF2) units into organic molecules.

Basic Information

Item	Details
Product Name	3-Bromo-3,5-Difluoropropanal Diethyl Acetal
CAS No.	1645-58-5
Molecular Formula	C7H13BrF2O2
Molecular Weight	247.08 g/mol
Synonyms	1-Bromo-3,3-diethoxy-1,1-difluoropropane; 3-Bromo-3,5-difluoropropionaldehyde Diethyl Acetal; Diethyl (3-Bromo-3,5-difluoropropanal) Acetal; 1,1-Difluoro-3-bromo-3-diethoxypropane; 3-Bromo-1,1-difluoro-3-diethoxypropane; 3,5-Difluoro-3-bromopropanal Diethyl Acetal; Propionaldehyde, 3-bromo-3,5-difluoro-, diethyl acetal
EINECS	Contact for details

Quality Control

Our 3-Bromo-3,5-Difluoropropanal Diethyl Acetal is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.