Description

4-Nitrophenol-1,2,6-13C3 is a stable isotope-labeled analog of 4-nitrophenol, specifically enriched with carbon-13 at the 1, 2, and 6 positions. This compound is an essential internal standard and tracer in advanced analytical chemistry, enabling precise quantification and metabolic pathway elucidation. It is primarily utilized by research institutions, pharmaceutical developers, and environmental testing laboratories engaged in mass spectrometry-based studies, including LC-MS and GC-MS, for method validation and complex mixture analysis.

Application

• Internal Standard for Quantitative Analysis: Used as a high-purity reference standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of unlabeled 4-nitrophenol in complex matrices.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer in pharmacokinetic and metabolic studies within pharmaceutical R&D to track the fate of phenolic compounds.
• Environmental Fate Studies: Employed in environmental science research to study the degradation, transformation, and transport of nitrophenol contaminants using isotope dilution techniques.
• Analytical Method Development: Critical for developing and validating sensitive and specific analytical methods in regulatory and quality control laboratories.
• Biochemical Research: Used in enzyme activity assays (e.g., for phosphatases) where 4-nitrophenol is a product, allowing for precise kinetic measurements with minimal interference.
• Isotope Labeling Synthesis: Acts as a labeled building block for the synthesis of more complex 13C-labeled organic compounds for research purposes.

Basic Information

Product Name	4-Nitrophenol-1,2,6-13C3
CAS No.	93628-02-5
Molecular Formula	C313C3H5NO3
Molecular Weight	142.04 (for 13C3 labeled form)
Synonyms	4-Nitrophenol-13C3; p-Nitrophenol-1,2,6-13C3; 4-Hydroxynitrobenzene-13C3; PNP-13C3; 1-Hydroxy-4-nitrobenzene-13C3; NSC 41648-13C3; 4-Nitro-1-hydroxybenzene-13C3
EINECS	Contact for details

Quality Control

Our 4-Nitrophenol-1,2,6-13C3 is manufactured under strict quality-controlled conditions to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity by HPLC, and identity confirmation by spectroscopic methods. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance in your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99% (on the labeled positions)
Chemical Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98%
Solubility	Soluble in organic solvents (e.g., methanol, ethanol, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.