Description

(22R)-3β-(α-D-Galactopyranosyloxy)-2β,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One is a high-purity, complex steroidal glycoside of significant interest in advanced research and development. This compound serves as a critical reference standard and a valuable pharmacological intermediate for exploring novel therapeutic pathways. It is primarily sought by the pharmaceutical, biotechnology, and academic research sectors for its potential bioactivity.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification in analytical method development and quality control (QC/QA) of related drug substances.
• Biochemical Research: Serves as a key intermediate or probe in studying steroid biosynthesis, receptor interactions, and signal transduction pathways.
• Drug Discovery & Development: Acts as a starting material or a synthetic precursor for the creation of novel steroidal derivatives with potential therapeutic applications.
• Academic & Contract Research: Utilized in universities and CROs for fundamental research into natural product chemistry, glycoside activity, and metabolic studies.
• Analytical Method Validation: Employed as a certified material to validate HPLC, LC-MS, and other chromatographic assays in compliance with ICH guidelines.

Basic Information

Product Name	(22R)-3β-(α-D-Galactopyranosyloxy)-2β,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One
CAS No.	93552-68-2
Molecular Formula	C33H56O11
Molecular Weight	628.80 g/mol
Synonyms	22R-Hydroxy-Withanolide G; 3-O-β-D-Galactopyranosyl-(22R)-2β,14α,20β,22,25-pentahydroxy-5β-cholest-7-en-6-one; Withanolide G 3-O-β-D-galactoside; Ajugalactone galactoside; (22R)-Withanolide G galactoside; 93552-68-2; Pentahydroxycholestenone galactoside
EINECS	Contact for details

Quality Control

Our production of (22R)-3β-(α-D-Galactopyranosyloxy)-2β,14,20,22,25-Pentahydroxy-5β-Cholest-7-En-6-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic and must be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.