Description

8-Deacetyl-Yunaconitine is a high-purity diterpenoid alkaloid derived from specific Aconitum species, serving as a critical reference standard and research compound. Its precise chemical structure makes it an invaluable tool for analytical method development, phytochemical research, and pharmacological studies. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focused on natural product chemistry and toxicology.

Application

• Phytochemical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of Aconitum alkaloids in herbal products and traditional medicines.
• Pharmacological Research: Serves as a key intermediate or probe in studies investigating the structure-activity relationships (SAR) of diterpenoid alkaloids, particularly their effects on ion channels.
• Analytical Method Development: Essential for developing and validating chromatographic methods (e.g., HPLC, LC-MS) for the detection and quantification of related alkaloids in complex matrices.
• Toxicology Studies: Employed in forensic and clinical toxicology to understand the metabolism and toxicokinetics of Aconitum-derived compounds.
• Natural Product Isolation & Synthesis: Acts as a benchmark in the isolation, purification, and semi-synthetic modification of complex plant alkaloids.
• Quality Control in Herbal Medicine: Used to establish specifications and ensure batch-to-batch consistency in the manufacture of standardized botanical extracts.

Basic Information

Product Name	8-Deacetyl-Yunaconitine
CAS No.	93460-55-0
Molecular Formula	C32H43NO9
Molecular Weight	585.69 g/mol
Synonyms	8-Deacetylyunaconitine; Yunaconitine, 8-deacetyl-; 8-Deacetyl-yunaconitine; (1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol 8-acetate 14-benzoate (related); Aconitum alkaloid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 8-Deacetyl-Yunaconitine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research and analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant guidelines for reference standards, and specifications can be aligned with customer requirements for specific research or quality control purposes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.