Description

5,14,15-Trihydroxy-6,8,10,12-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a member of the hydroxy fatty acid class with significant biological signaling properties. This compound is valued for its role as a key intermediate and reference standard in advanced biochemical and pharmaceutical research. It is primarily required by research institutions and manufacturers in the life sciences sector for studying inflammatory pathways, lipid metabolism, and developing novel therapeutic agents.

Application

• Biochemical Research Standard: Used as a high-purity reference material in analytical laboratories for method development and validation in lipidomics studies.
• Pharmaceutical R&D: Serves as a critical intermediate or lead compound in the development of drugs targeting inflammation, immune response, and metabolic disorders.
• Cell Signaling Studies: Employed in in-vitro and in-vivo research to investigate the mechanisms of eicosanoid-mediated cellular communication and signal transduction.
• Enzymology: Acts as a substrate or product in enzymatic assays for studying the activity of lipoxygenases, cyclooxygenases, and other related enzymes.
• Academic Research: Utilized in university and institutional labs for fundamental research into the biochemistry of polyunsaturated fatty acid derivatives.

Basic Information

Product Name	5,14,15-Trihydroxy-6,8,10,12-Eicosatetraenoic Acid
CAS No.	92950-25-9
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5,14,15-TriHETE; 5,14,15-Trihydroxyeicosatetraenoic Acid; (5Z,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxyicosa-6,8,10,12-tetraenoic acid; 5,14,15-THETA; 5,14,15-Trihydroxy-6,8,10,12-eicosatetraenoate; Lipoxin isomer; Eicosanoid derivative
EINECS	Contact for details

Quality Control

Our 5,14,15-Trihydroxy-6,8,10,12-Eicosatetraenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with stated specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.