Description

Pravadoline CAS NO 92623-83-1 is a synthetic cannabinoid receptor agonist of significant interest in pharmacological research and development. Its primary value lies in its selective activity, making it a crucial reference compound for studying the endocannabinoid system and related therapeutic pathways. This product is essential for pharmaceutical R&D laboratories, academic institutions, and analytical facilities focused on neuropharmacology, pain management, and receptor characterization.

Application

• Pharmacological Reference Standard: Used as a high-purity analytical standard in cannabinoid receptor binding assays and activity studies.
• Medicinal Chemistry Research: Serves as a key intermediate or lead compound in the development of novel analgesic and neuroprotective agents.
• Biochemical Pathway Analysis: Employed in vitro and in vivo to investigate the signaling mechanisms of the CB1 and CB2 receptors.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting studies on the endocannabinoid system.
• Drug Discovery & Development: Utilized in high-throughput screening (HTS) and structure-activity relationship (SAR) studies for new therapeutic candidates.
• Analytical Method Development: Acts as a calibrant or control substance in developing and validating HPLC, LC-MS, and GC-MS methods for cannabinoid analysis.

Basic Information

Product Name	Pravadoline
CAS No.	92623-83-1
Molecular Formula	C24H30N2O3
Molecular Weight	394.51 g/mol
Synonyms	WIN 48098; 4-Methoxy-3-(2-methyl-1-piperidinylmethyl)-1,2-diphenyl-1H-indole; 1-[2-(4-Methoxyphenyl)ethyl]-2-methyl-3-(1-piperidinylmethyl)-1H-indole; Pravadoline maleate (salt form); Pravadoline hydrochloride (salt form); (4-Methoxyphenyl)-[2-methyl-1-(2-piperidin-1-ylethyl)indol-3-yl]methanone (alternative representation)
EINECS	Contact for details

Quality Control

Our Pravadoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity assay, identity confirmation via IR and MS, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.