Description

Meclofenamate Sodium is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class. This compound is valued for its potent inhibition of cyclooxygenase (COX) enzymes, which are key mediators of inflammation and pain. It serves as a critical active pharmaceutical ingredient (API) and reference standard for manufacturers and research institutions in the pharmaceutical and life sciences sectors.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of prescription anti-inflammatory and analgesic medications.
• Utilized as a pharmacological research tool for studying COX enzyme pathways, inflammation mechanisms, and pain management.
• Serves as a certified reference standard in analytical laboratories for quality control and method validation (HPLC, LC-MS).
• Key component in preclinical and clinical studies for developing new therapeutic agents targeting inflammatory diseases.
• Used in the synthesis of derivative compounds for structure-activity relationship (SAR) studies in medicinal chemistry.

Basic Information

Product Name	Meclofenamate Sodium
CAS No.	6385-02-0
Molecular Formula	C14H10Cl2NNaO2
Molecular Weight	318.13 g/mol
Synonyms	Meclofenamic Acid Sodium Salt; Sodium Meclofenamate; N-(2,6-Dichloro-m-tolyl)anthranilic Acid Sodium Salt; CL-583; Arquel; Meclomen; 2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic Acid Sodium Salt
EINECS	228-985-8

Quality Control

Our Meclofenamate Sodium is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.