Description

Ibuprofen CAS NO 15687-27-1 is a widely recognized non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class. Its primary value lies in its potent analgesic, anti-inflammatory, and antipyretic properties, making it a cornerstone active pharmaceutical ingredient (API). This compound is essential for manufacturers in the pharmaceutical industry, particularly for the production of over-the-counter (OTC) pain relievers, prescription medications for chronic conditions like arthritis, and veterinary formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in tablets, capsules, and liquid formulations for pain, fever, and inflammation relief.
• Analgesic Formulations: Manufacturing of OTC and prescription medications for headaches, dental pain, menstrual cramps, and minor injuries.
• Anti-inflammatory Medications: Production of drugs for managing chronic inflammatory conditions such as rheumatoid arthritis and osteoarthritis.
• Antipyretic Drugs: Key component in fever-reducing medications for adults and children.
• Veterinary Pharmaceuticals: Used in formulations for pain and inflammation management in animals.
• Topical Preparations: Incorporated into gels and creams for localized pain relief.
• Combination Drug Products: Used in fixed-dose combination therapies with other APIs like pseudoephedrine or paracetamol.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for new drug delivery systems.

Basic Information

Product Name	Ibuprofen
CAS No.	15687-27-1
Molecular Formula	C13H18O2
Molecular Weight	206.28 g/mol
Synonyms	2-(4-Isobutylphenyl)propanoic Acid; (±)-Ibuprofen; p-Isobutylhydratropic Acid; 4-Isobutyl-α-methylphenylacetic Acid; Advil™ (brand name API); Motrin™ (brand name API); Nurofen™ (brand name API); (+/-)-Ibuprofen
EINECS	239-784-6

Quality Control

Our Ibuprofen is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, BP, and JP. Every batch undergoes comprehensive analytical testing including identification, assay, and impurity profiling to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting purity, related substances, residual solvents, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, typically between 15°C and 25°C (59°F and 77°F), in a dry, well-ventilated area. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Rotation	-0.05° to +0.05°
Melting Point	75°C - 78°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.