Description

Clofenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) belonging to the fenamate class, known for its potent cyclooxygenase (COX) inhibitory activity. This compound serves as a critical pharmaceutical intermediate and a valuable reference standard in analytical and pharmacological research. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and academic sectors requiring high-purity active pharmaceutical ingredients (APIs) and biochemical tools.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced anti-inflammatory drug candidates.
• Biochemical Research: Used as a reference standard and tool compound in studies of prostaglandin biosynthesis, COX enzyme inhibition, and inflammatory pathways.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in HPLC, LC-MS, and other analytical techniques.
• Pharmacology Studies: Employed in *in vitro* and *in vivo* models to investigate the efficacy and mechanisms of fenamate-class NSAIDs.
• Academic & Industrial R&D: Utilized in discovery chemistry and medicinal chemistry programs targeting inflammation-related disorders.

Basic Information

Product Name	Clofenamic Acid
CAS No.	13278-36-9
Molecular Formula	C13H10ClNO2
Molecular Weight	247.68 g/mol
Synonyms	2-[(3-Chlorophenyl)amino]benzoic acid; N-(3-Chlorophenyl)anthranilic acid; Clofenamate; Clofenamic Acid; NSC 113029; BA 4114A; Fenamic Acid, 3'-Chloro-; 3'-Chloro-2,3-diphenylaminobenzoic Acid (common misnomer)
EINECS	Contact for details

Quality Control

Our Clofenamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.