Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphopropanol (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylpropanolamine analog. This compound is a critical building block in advanced lipid research and formulation, valued for its defined structure and consistent quality. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid components for developing liposomal drug delivery systems, lipid nanoparticles (LNPs), and biomimetic membranes.

Application

• Liposomal Drug Delivery: A key phospholipid component for constructing stable, functionalized liposomes for targeted therapeutic delivery.
• Lipid Nanoparticle (LNP) Formulation: Used in the development of mRNA and siRNA delivery vehicles, contributing to particle stability and fusogenic properties.
• Biomimetic Membrane Research: Serves as a model lipid for studying membrane biophysics, protein-lipid interactions, and cellular membrane dynamics.
• Surface Modification & Coatings: Employed to create biocompatible coatings on medical devices or sensors due to its phospholipid headgroup.
• Diagnostic Reagent Development: Utilized in the formulation of lipid-based reagents for diagnostic assays and imaging probes.
• Excipient in Advanced Formulations: Acts as a functional excipient in niche pharmaceutical formulations requiring specific lipid matrices.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphopropanol (Sodium Salt)
CAS No.	92609-91-1
Molecular Formula	C37H72NNaO8P
Molecular Weight	712.93 g/mol
Synonyms	DPPP (Sodium Salt); 1,2-Dihexadecanoyl-sn-glycero-3-phospho-N-propanol (Sodium Salt); Sodium 1,2-dipalmitoyl-sn-glycero-3-phosphopropanol; Phosphatidylpropanolamine, DPPA analog; 1,2-Dipalmitoylphosphatidylpropanolamine; 3-sn-Phosphatidylpropanolamine, 1,2-dipalmitoyl derivative; Lipid 1600 PC-3-PPNa
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphopropanol (Sodium Salt) is manufactured under strict quality systems to ensure the high purity and consistency required for research and cGMP applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material suitable for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 10 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.