Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphomethanol (Sodium Salt) is a high-purity synthetic phospholipid derivative, specifically a phosphatidylmethanol analogue, widely used as a critical intermediate and functional excipient in advanced pharmaceutical and biotechnological formulations. Its value lies in its defined chemical structure and consistent quality, which are essential for research and development in drug delivery systems, particularly for enhancing the stability and efficacy of lipid-based nanoparticles. This product is primarily needed by manufacturers and researchers in the pharmaceutical, cosmetic, and life science industries working on liposomal drug carriers, diagnostic agents, and novel biomaterials.

Application

• Lipid Nanoparticle (LNP) Formulation: A key phospholipid component in the development of mRNA and siRNA delivery systems, including those used for vaccines and gene therapies.
• Liposome and Niosome Production: Used as a structural lipid to create stable vesicles for the encapsulation and targeted delivery of active pharmaceutical ingredients (APIs).
• Biomembrane Research: Serves as a model membrane lipid in biophysical studies to investigate membrane fluidity, permeability, and protein-lipid interactions.
• Diagnostic Reagent Preparation: Employed in the formulation of contrast agents and other diagnostic tools that require specific lipid assemblies.
• Cosmetic Actives Carrier: Functions as an advanced delivery vehicle in high-end cosmetic products for improved skin penetration of vitamins and antioxidants.
• Bioconjugation and Surface Modification: The reactive headgroup allows for chemical modification, making it useful for creating functionalized surfaces or conjugating targeting ligands.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphomethanol (Sodium Salt)
CAS No.	92609-89-7
Molecular Formula	C36H72NaO9P
Molecular Weight	702.91 g/mol
Synonyms	DPPM-Na; 1,2-Dihexadecanoyl-sn-glycero-3-phospho(methanol) (sodium salt); Phosphatidylmethanol, dipalmitoyl, sodium salt; Sodium 1,2-dipalmitoyl-sn-glycero-3-phosphomethanol; 1,2-Dipalmitoylphosphatidylmethanol sodium salt; sn-Glycero-3-phosphomethanol, 1,2-dipalmitoyl, sodium salt; L-α-Phosphatidylmethanol, dipalmitoyl, sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphomethanol (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specific batch results are available upon request, supporting compliance with cGMP and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.