Description

L-α-Phosphatidylethanolamine, Dipalmitoyl, NBD is a high-purity, fluorescently labeled phospholipid derivative, specifically engineered for advanced research applications. This compound matters as a critical tool for probing membrane dynamics, lipid trafficking, and cellular processes due to its NBD fluorophore, which provides excellent sensitivity for fluorescence-based detection. It is essential for researchers and developers in the life sciences, particularly in biochemistry, cell biology, and pharmaceutical development, where precise visualization of lipid behavior is required.

Application

• Biomembrane Research: As a fluorescent probe for studying lipid bilayer structure, fluidity, and phase transitions in model membranes (e.g., liposomes, supported lipid bilayers).
• Cellular Trafficking Studies: Tracing the intracellular movement, metabolism, and sorting of phosphatidylethanolamine within living cells.
• Lipoprotein Analysis: Investigating the assembly, remodeling, and metabolism of lipoproteins in cardiovascular and metabolic disease research.
• Drug Delivery System Development: A functional component in the formulation and characterization of lipid-based nanoparticle carriers (e.g., liposomes, micelles) for targeted therapeutic delivery.
• Enzyme Activity Assays: Serving as a specific fluorescent substrate for phospholipases and other lipid-modifying enzymes to measure kinetic parameters and inhibitor screening.
• Apoptosis & Autophagy Research: Monitoring the externalization of phosphatidylethanolamine, a key marker during programmed cell death processes.

Basic Information

Product Name	L-α-Phosphatidylethanolamine, Dipalmitoyl, NBD
CAS No.	92605-64-6
Molecular Formula	C72H123N4O16P
Molecular Weight	1355.76 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); DPPE-NBD; NBD-DPPE; 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; Fluorescent DPPE; NBD PE; NBD-labeled phosphatidylethanolamine
EINECS	Contact for details

Quality Control

Every batch of our L-α-Phosphatidylethanolamine, Dipalmitoyl, NBD is produced and analyzed under strict quality protocols to ensure the highest standard of purity and performance for research. We employ advanced chromatographic (HPLC) and spectroscopic techniques to verify identity, purity, and fluorescent properties. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, confirming compliance with our rigorous in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98% (Area Percent)
Fluorescence Properties	Excitation ~460 nm, Emission ~534 nm (in chloroform)
Solubility	Soluble in chloroform, methanol, DMSO; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.