Description

1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Ethanone is a high-purity organic compound featuring a piperazine core linked to an acetophenone derivative, serving as a critical building block in advanced chemical synthesis. Its bifunctional structure, combining an aromatic amine with a ketone-substituted piperazine, makes it a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, receptor modulators, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require specific piperazine-based architectures.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in OLED displays and lighting due to its conjugated amine structure.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and high-performance pigments.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, catalysis, and material science applications.
• Ligand Synthesis for Catalysis: Used to create complex ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Ethanone
CAS No.	92394-00-8
Molecular Formula	C12H17N3O
Molecular Weight	219.29 g/mol
Synonyms	1-[4-(4-Aminophenyl)piperazin-1-yl]ethanone; 1-[4-(4-Amino-phenyl)-1-piperazinyl]ethanone; N-(4-Aminophenyl)-N'-(acetyl)piperazine; 4'-Amino-1-acetylpiperazine; 1-Acetyl-4-(4-aminophenyl)piperazine; Ethanone, 1-[4-(4-aminophenyl)-1-piperazinyl]-; 92394-00-8
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.