Description

(2R)-2-{[(tert-Butoxy)Carbonyl]Amino}Octanoic Acid CAS NO 92211-96-6 is a high-purity, chiral amino acid derivative featuring a Boc-protected amine group and a medium-length alkyl chain. This compound serves as a critical chiral building block in the synthesis of complex peptides, peptidomimetics, and active pharmaceutical ingredients (APIs), enabling precise control over stereochemistry. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs, protease inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a hydrophobic, Boc-protected amino acid residue.
• Agrochemical Research: Serves as a building block for developing chiral active ingredients with specific biological activity.
• Bioconjugation & Linker Chemistry: The carboxylic acid and protected amine functionalities allow for conjugation to other molecules, polymers, or surfaces.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of enzyme substrates, inhibitors, and molecular probes.
• Material Science: A precursor for creating functionalized polymers and surfaces with specific chiral properties.

Basic Information

Product Name	(2R)-2-{[(tert-Butoxy)Carbonyl]Amino}Octanoic Acid
CAS No.	92211-96-6
Molecular Formula	C₁₃H₂₅NO₄
Molecular Weight	259.34 g/mol
Synonyms	Boc-D-norleucine; (R)-2-((tert-Butoxycarbonyl)amino)octanoic acid; Boc-D-Nle-OH; D-2-Aminooctanoic acid N-Boc derivative; N-(tert-Butoxycarbonyl)-D-norleucine; N-Boc-D-norleucine; (R)-N-Boc-2-aminooctanoic acid; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]octanoic acid
EINECS	Contact for details

Quality Control

Our (2R)-2-{[(tert-Butoxy)Carbonyl]Amino}Octanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.