Description

5(S)-Hepe is a specialized, high-purity eicosapentaenoic acid (EPA) derivative, specifically the 5(S)-hydroxy form, with the CAS registry number 92008-51-0. This compound serves as a critical biochemical reference standard and a key synthetic intermediate in advanced research and development. It is essential for pharmaceutical, nutraceutical, and life science organizations focused on lipid mediator research, inflammation studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a high-purity reference standard in lipidomics and metabolomics studies.
• Pharmaceutical R&D: Serves as a key intermediate in the synthesis of specialized pro-resolving mediators (SPMs) and other bioactive lipid compounds.
• Inflammation & Immunology Studies: Critical for investigating the 5-lipoxygenase pathway and the role of hydroxyeicosapentaenoic acids in inflammatory processes.
• Analytical Method Development: Employed for calibrating HPLC, LC-MS, and GC-MS systems in analytical laboratories.
• Nutraceutical Research: Used in studies exploring the advanced benefits and mechanisms of ω-3 fatty acid derivatives.
• Academic Research: A vital tool for universities and research institutes conducting fundamental research in biochemistry and cell signaling.

Basic Information

Product Name	5(S)-Hepe
CAS No.	92008-51-0
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	5(S)-HETE; 5(S)-Hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic Acid; 5(S)-HETE; (5S)-Hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoic Acid; 5S-Hydroxyeicosatetraenoic Acid; 5(S)-HEPE; 5S-HEPE
EINECS	Contact for details

Quality Control

Our 5(S)-Hepe is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be developed to meet specific research or GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area %)
Purity (HPLC)	≥ 98% (Total Area %)
Enantiomeric Purity (Chiral HPLC)	≥ 99% 5(S)-isomer
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.