Description

2-Bromo-6-Methoxypyrazine is a versatile halogenated pyrazine derivative, a key building block in advanced organic synthesis. Its value lies in its reactive bromine atom and methoxy substituent, which enable precise functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyrazine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Scale-Up: A fundamental reagent for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	2-Bromo-6-Methoxypyrazine
CAS No.	91678-76-1
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	6-Methoxy-2-bromopyrazine; 2-Bromo-6-methoxypyrazine; Pyrazine, 2-bromo-6-methoxy-; 2-Brom-6-methoxypyrazin (German); 2-ブロモ-6-メトキシピラジン (Japanese); 2-溴-6-甲氧基吡嗪 (Chinese); Bromomethoxypyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Methoxypyrazine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.