Description

2-Amino-5-Iodo-3-Methylpyrazine is a halogenated pyrazine derivative, a versatile and high-value heterocyclic building block. Its unique structure, featuring both an amino group and an iodine atom, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by academic and industrial chemists in material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyrazine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or photoactive compounds.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Amino-5-Iodo-3-Methylpyrazine
CAS No.	91416-90-9
Molecular Formula	C5H6IN3
Molecular Weight	235.03 g/mol
Synonyms	3-Methyl-5-iodopyrazin-2-amine; 5-Iodo-3-methylpyrazin-2-amine; 2-Amino-3-methyl-5-iodopyrazine; 5-Iodo-3-methyl-2-pyrazinamine; 91416-90-9; AI3-52030; CTK8G7135; ZINC000103049777; AKOS040759915
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Iodo-3-Methylpyrazine is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.