Description

1-o-Hexadecyl-2-o-Benzyl-Sn-Glycero-3-Phosphocholine is a synthetic, structured phospholipid analog, specifically a benzyl-protected lysophosphatidylcholine derivative. This compound is a critical high-purity intermediate and research tool for the development of novel lipid-based drug delivery systems and biomembrane studies. It is primarily utilized by pharmaceutical R&D teams and academic research laboratories focused on liposome formulation, prodrug synthesis, and investigating lipid metabolism and signaling pathways.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: As a functionalized lipid component for creating targeted or stealth liposomal carriers for drug and gene delivery.
• Pharmaceutical Intermediate: Key building block in the synthetic pathway for more complex phospholipid-based active pharmaceutical ingredients (APIs) or prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to phospholipases and other lipid-modifying enzymes.
• Membrane Biophysics: A tool for studying the properties and dynamics of artificial lipid bilayers and membrane models.
• Cell Biology & Signaling: Investigation of the role of specific lysophospholipids in cellular processes and signal transduction mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in lipidomics.

Basic Information

Product Name	1-o-Hexadecyl-2-o-Benzyl-Sn-Glycero-3-Phosphocholine
CAS No.	91326-84-0
Molecular Formula	C₃₃H₆₂NO₆P
Molecular Weight	599.82 g/mol
Synonyms	1-Hexadecyl-2-benzyl-sn-glycero-3-phosphocholine; 2-Benzyl-1-hexadecyl-sn-glycero-3-phosphocholine; Benzyl-LPC C16:0; 1-O-Hexadecyl-2-O-benzyl-sn-glycero-3-phosphocholine; LysoPC(16:0/0:0[2-OBz]); Lysophosphatidylcholine, 1-hexadecyl-2-benzyl derivative; sn-Glycero-3-phosphocholine, 1-hexadecyl-2-benzyl ether
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-o-Benzyl-Sn-Glycero-3-Phosphocholine is produced under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to support research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.