Description

Dnp-α-Aminoisobutyric Acid is a specialized amino acid derivative, primarily used as a key intermediate and protecting group reagent in advanced organic synthesis. Its value lies in enabling precise peptide modifications and facilitating complex molecular construction, which is critical for research and development. This compound is essential for pharmaceutical researchers, peptide chemists, and biotechnology companies focused on developing novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis Intermediate: Acts as a crucial building block for incorporating the non-proteinogenic amino acid, 2-aminoisobutyric acid (Aib), into peptide chains.
• Protecting Group Chemistry: The dinitrophenyl (Dnp) group serves as a temporary protecting group for amino functions during multi-step synthetic sequences.
• Pharmaceutical Research: Used in the development and study of peptidomimetics and constrained peptides with potential therapeutic applications.
• Biochemical Tool Development: Employed in the synthesis of specialized probes, substrates, and inhibitors for enzymatic and receptor studies.
• Material Science: Potential use in creating novel bio-inspired polymers and foldamers with unique structural properties.

Basic Information

Product Name	Dnp-α-Aminoisobutyric Acid
CAS No.	90841-06-8
Molecular Formula	C11H13N3O6
Molecular Weight	283.24 g/mol
Synonyms	2-[(2,4-Dinitrophenyl)amino]-2-methylpropanoic Acid; N-(2,4-Dinitrophenyl)-2-aminoisobutyric Acid; DNP-Aib-OH; Dnp-Aminoisobutyric Acid; N-Dnp-2-aminoisobutyric Acid; 2-Methyl-2-[(2,4-dinitrophenyl)amino]propanoic Acid; Aib(Dnp)
EINECS	Contact for details

Quality Control

Our Dnp-α-Aminoisobutyric Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. It is also easily oxidized; for long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.