Description

p-Methylacetophenone 2,4-Dinitrophenylhydrazone is a high-purity chemical derivative primarily used as a key analytical standard and reagent. This compound is essential for the precise identification and quantification of carbonyl compounds, particularly ketones, in complex matrices. It is critically important for quality control laboratories, research institutions, and manufacturers in the pharmaceutical, agrochemical, and fine chemical synthesis sectors who require reliable and consistent analytical results.

Application

• Analytical Reference Standard: Used in HPLC, GC, and spectrophotometric methods for the calibration and validation of assays targeting carbonyl groups.
• Derivatization Reagent: Essential for converting volatile or hard-to-detect ketones and aldehydes into stable, chromophoric 2,4-dinitrophenylhydrazone (DNPH) derivatives for enhanced analysis.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of ketone-based impurities or degradation products in active pharmaceutical ingredients (APIs).
• Environmental Testing: Applied in the analysis of airborne carbonyl compounds and other environmental pollutants.
• Organic Synthesis Intermediate: Serves as a protected or functionalized intermediate in multi-step synthetic routes for specialized chemicals.
• Food and Flavor Analysis: Used in the quality control of flavors, fragrances, and food products where specific ketones are markers of quality or authenticity.

Basic Information

Product Name	p-Methylacetophenone 2,4-Dinitrophenylhydrazone
CAS No.	1237-49-6
Molecular Formula	C15H14N4O4
Molecular Weight	314.30 g/mol
Synonyms	1-(4-Methylphenyl)ethanone 2,4-dinitrophenylhydrazone; 4'-Methylacetophenone 2,4-DNPH; p-Acetyltoluene 2,4-dinitrophenylhydrazone; 4-Methylacetophenone 2,4-dinitrophenylhydrazone; DNPH derivative of 4'-Methylacetophenone; 2,4-Dinitrophenylhydrazone of p-Methylacetophenone; (E)-1-(4-Methylphenyl)ethan-1-one 2-(2,4-dinitrophenyl)hydrazone
EINECS	Contact for details

Quality Control

Our p-Methylacetophenone 2,4-Dinitrophenylhydrazone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting requirements for use as an analytical standard. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.