Description

Dansyl-Glycine CAS NO 1091-85-6 is a high-purity, fluorescent-labeled amino acid derivative, widely recognized for its utility as a key intermediate and analytical reagent. Its primary value lies in its strong fluorescence properties, making it an essential tool for tagging, detection, and quantification in sensitive analytical workflows. This compound is critical for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable, high-quality reagents for method development and quality control.

Application

• Fluorescent Labeling Agent: Used for the derivatization and sensitive detection of amino acids, peptides, and other biomolecules in HPLC and capillary electrophoresis.
• Biochemical Research: Serves as a critical intermediate in the synthesis of fluorescent probes and tags for studying protein structure, function, and interactions.
• Pharmaceutical Analysis: Employed in the development and validation of analytical methods for the quantification of active pharmaceutical ingredients (APIs) and related substances.
• Proteomics & Metabolomics: Utilized in sample preparation workflows for labeling low-abundance analytes to enhance detection limits in mass spectrometry and other advanced analytical platforms.
• Diagnostic Reagent Manufacturing: Acts as a key component in formulating reagents for clinical diagnostic kits that rely on fluorescence-based detection.
• Quality Control Standard: Provides a certified reference material for calibrating instruments and ensuring the accuracy of analytical methods in quality control laboratories.

Basic Information

Product Name	Dansyl-Glycine
CAS No.	1091-85-6
Molecular Formula	C14H14N2O4S
Molecular Weight	306.34 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonylglycine; Dansylglycine; Glycine, N-[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-; N-Dansylglycine; 1-Dimethylaminonaphthalene-5-sulfonylglycine; DNSC-Gly-OH; N-(5-Dimethylaminonaphthalene-1-sulfonyl)glycine
EINECS	214-132-2

Quality Control

Our Dansyl-Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to relevant industry standards and can provide material suitable for research and development under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.