Description

Atosiban is a synthetic peptide and a competitive antagonist of the hormone oxytocin, specifically designed to inhibit premature uterine contractions. This compound is of critical importance in pharmaceutical development for the management of preterm labor, offering a targeted therapeutic approach. It is primarily required by pharmaceutical manufacturers, research institutions, and clinical laboratories engaged in the development and production of tocolytic agents. Atosiban CAS NO 90779-69-4 represents a high-purity active pharmaceutical ingredient (API) essential for ensuring the efficacy and safety of final drug formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the inhibition of premature labor (tocolysis).
• Clinical Research: Used in preclinical and clinical studies to investigate uterine physiology and the mechanisms of preterm birth.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical method development in pharmaceutical labs.
• Biochemical Research: Employed in studies of oxytocin and vasopressin receptor interactions and signaling pathways.
• Drug Development: A key intermediate or target molecule for developing new tocolytic agents and related peptide therapeutics.

Basic Information

Product Name	Atosiban
CAS No.	90779-69-4
Molecular Formula	C43H67N11O12S2
Molecular Weight	994.2 g/mol
Synonyms	1-(3-Mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithine-oxytocin; Tractocile; Antocin; RWJ 22164; d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH2(9)]OVT; Oxytocin antagonist; Barusiban (related analog)
EINECS	Contact for details

Quality Control

Our Atosiban is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral purity assessment, residual solvent analysis, and identity confirmation by mass spectrometry and NMR. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing compliance with in-house specifications developed for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.