Description

2-Amino-5-Bromo-3-Piperidin-1-Ylpyrazine is a high-purity, heterocyclic organic compound featuring a brominated pyrazine core substituted with amino and piperidine functional groups. This specific molecular architecture makes it a critical building block (advanced intermediate) for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, especially in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced molecules for crop protection and pesticide development.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	2-Amino-5-Bromo-3-Piperidin-1-Ylpyrazine
CAS No.	90674-84-3
Molecular Formula	C9H14BrN5
Molecular Weight	256.15 g/mol
Synonyms	5-Bromo-2-amino-3-(1-piperidinyl)pyrazine; 3-(Piperidin-1-yl)-5-bromopyrazin-2-amine; 2-Amino-5-bromo-3-(1-piperidinyl)pyrazine; 5-Bromo-3-piperidin-1-ylpyrazin-2-amine; 90674-84-3; 2-Pyrazinamine, 5-bromo-3-(1-piperidinyl)-; 5-Bromo-2-amino-3-piperidin-1-yl-pyrazine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Piperidin-1-Ylpyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.