Description

1-Piperazineacetamide,4-(2-Hydroxyethyl)-(7Ci) CAS NO 90228-11-8 is a specialized piperazine derivative, a high-value intermediate of significant interest in advanced organic synthesis. Its molecular structure, featuring both an acetamide and a hydroxyethyl side chain, makes it a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapies due to its functional groups suitable for conjugation.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce functional amine and hydroxyl groups into polymer backbones, enhancing material properties.
• Biochemical Research: Used as a standard or reagent in proteomics and enzyme inhibition studies.
• Agrochemical Development: Functions as an intermediate in the research and synthesis of new-generation crop protection agents.

Basic Information

Product Name	1-Piperazineacetamide,4-(2-Hydroxyethyl)-(7Ci)
CAS No.	90228-11-8
Molecular Formula	C8H17N3O2
Molecular Weight	187.24 g/mol
Synonyms	4-(2-Hydroxyethyl)piperazine-1-acetamide; 1-Acetamido-4-(2-hydroxyethyl)piperazine; N-(2-Hydroxyethyl)piperazineacetamide; 2-[4-(2-Hydroxyethyl)piperazin-1-yl]acetamide; 1-Piperazineacetamide, 4-(2-hydroxyethyl)-; HEAP; 90228-11-8; 4-(2-Hydroxyethyl)-1-piperazineacetamide
EINECS	Contact for details

Quality Control

Our 1-Piperazineacetamide,4-(2-Hydroxyethyl)-(7Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.