Description

1-Ethylpiperidine-4-Carboxylic Acid is a versatile piperidine derivative carboxylic acid, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, which allows for selective modification at both the carboxylic acid and the tertiary amine of the piperidine ring. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with central nervous system (CNS) activity or as a component of kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Precursor: The nitrogen atom can coordinate to metals, making it a useful precursor for designing chiral ligands or organocatalysts in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical spaces, structure-activity relationships (SAR), and library synthesis for high-throughput screening.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty materials requiring a functionalized piperidine core.

Basic Information

Product Name	1-Ethylpiperidine-4-Carboxylic Acid
CAS No.	90204-94-7
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	4-Carboxy-1-ethylpiperidine; 1-Ethyl-4-piperidinecarboxylic acid; 1-Ethylpiperidine-4-carboxylic acid; NSC 406165; 4-Piperidinecarboxylic acid, 1-ethyl-; 1-Ethylisonipecotic acid
EINECS	Contact for details

Quality Control

Our 1-Ethylpiperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates, including cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.