Description

Leukotriene A5 Methyl Ester is a specialized methyl ester derivative of the leukotriene A5 lipid mediator. This compound is of significant value as a critical biochemical standard and synthetic intermediate for research into eicosanoid signaling pathways and inflammatory processes. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and advanced diagnostic manufacturers engaged in the study of lipid metabolism, immunology, and respiratory diseases.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in analytical methods like HPLC and LC-MS for the quantification of leukotriene metabolites in biological samples.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel anti-inflammatory agents and leukotriene pathway modulators.
• Mechanistic Studies: Essential for in vitro and ex vivo studies investigating the role of leukotriene A5 and its derivatives in cellular signaling, inflammation, and immune response.
• Diagnostic Development: Employed in the development and calibration of immunoassays and diagnostic kits targeting specific eicosanoid biomarkers.
• Metabolic Pathway Analysis: A crucial tool for tracing metabolic fates and enzymatic transformations within the arachidonic acid cascade.

Basic Information

Product Name	Leukotriene A5 Methyl Ester
CAS No.	90121-06-5
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	LTA5 Methyl Ester; Methyl (5S,6S)-5,6-Epoxy-7,9,11,14-icosatetraenoate; (5S,6S)-5,6-Epoxy-7,9,11,14-eicosatetraenoic Acid Methyl Ester; 5,6-Oxido-7,9,11,14-eicosatetraenoic Acid Methyl Ester; Leukotriene A5 Methyl Ester; LTA5 Methyl Ester
EINECS	Contact for details

Quality Control

Our Leukotriene A5 Methyl Ester is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.