Description

Glucagon Hydrochloride (Human) is a highly purified polypeptide hormone, essential for regulating blood glucose levels. This critical pharmaceutical active ingredient is vital for the emergency treatment of severe hypoglycemia in diabetic patients. It is primarily utilized by pharmaceutical manufacturers in the production of injectable emergency kits and diagnostic agents. Our product, meeting exacting standards, ensures reliable performance and supply chain integrity for global healthcare applications.

Application

• Pharmaceutical Active Ingredient: Primary use in the formulation of emergency glucagon injection kits for severe hypoglycemia.
• Diagnostic Agent: Used in medical diagnostic procedures to assess pancreatic function and gastric motility.
• Biochemical Research: Serves as a critical reagent in endocrine and metabolic research studies.
• Reference Standard: Employed as a high-purity standard in quality control laboratories for analytical method development and validation.
• Therapeutic Development: Investigated for potential applications in new therapeutic areas beyond diabetes management.

Basic Information

Item	Detail
Product Name	Glucagon Hydrochloride (Human)
CAS No.	9007-92-5
Molecular Formula	C153H225N43O49S • xHCl
Molecular Weight	~3483 g/mol (monoisotopic, free base)
Synonyms	Glucagon HCl; Glucagon (Human); HGF; HG-Factor; Glukagon; 1H-Imidazole-4-propanoic acid, 5-oxo-L-prolyl-L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonyl-, hydrochloride (1:?); Pancreatic hyperglycemic hormone
EINECS	Contact for details

Quality Control

Our Glucagon Hydrochloride (Human) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, peptide mapping for identity, and stringent tests for related substances, bacterial endotoxins, and residual solvents to ensure it meets or exceeds relevant pharmacopeial standards (e.g., USP, EP). A Certificate of Analysis (COA) documenting all release specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or under refrigeration at 2-8°C as specified. The product is hygroscopic (moisture-sensitive) and must be protected from exposure to high humidity. For long-term stability, store in the original sealed container under inert conditions if necessary.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	NLT 95.0% and NMT 105.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities: NMT 5.0% Any individual impurity: NMT 2.0%
Water Content (KF)	NMT 10.0%
Bacterial Endotoxins	Less than 10.0 EU/mg
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.