Description

1,2-Dilinoleoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid characterized by its specific fatty acid composition. This compound is a critical component in advanced lipid-based formulations, offering superior biocompatibility and structural functionality. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and advanced material science sectors for developing innovative delivery systems and biomimetic membranes.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for creating stable, uniform liposomes and lipid nanoparticles (LNPs) for drug and gene delivery.
• Biomembrane Research: Used as a model membrane component in biophysical studies to investigate lipid bilayer properties, permeability, and protein-lipid interactions.
• Nutraceutical Encapsulation: Employed in the encapsulation of sensitive bioactive compounds, such as ω-3 fatty acids or antioxidants, to enhance stability and bioavailability.
• Cell Culture & Media Supplements: Serves as a defined lipid source in serum-free cell culture media for specialized cell lines.
• Diagnostic Reagent Development: Utilized in the formulation of reagents for diagnostic assays, including those based on membrane fusion or signal amplification.
• Cosmetic Actives Delivery: Incorporated into cosmetic formulations to improve the skin penetration and stability of active ingredients.

Basic Information

Product Name	1,2-Dilinoleoyl-Sn-Glycero-3-Phosphocholine
CAS No.	998-06-1
Molecular Formula	C44H80NO8P
Molecular Weight	782.08 g/mol
Synonyms	DLinoleoyl Phosphatidylcholine; 1,2-Dilinoleoylphosphatidylcholine; PC(18:2/18:2); (2R)-2,3-Bis[[(9Z,12Z)-octadeca-9,12-dienoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; Phosphatidylcholine, 1,2-di-(9Z,12Z-octadecadienoyl)-; DLPC (ambiguous, can refer to dilauroyl); 1,2-Di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Dilinoleoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets stringent specifications for research and cGMP-grade applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Linoleic acid ≥ 95% of total fatty acids
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.