Description

Ailanthone CAS NO 981-15-7 is a natural quassinoid compound primarily isolated from the tree of heaven (*Ailanthus altissima*). This compound is of significant interest due to its potent and selective biological activities, particularly its anti-cancer and anti-protozoal properties. It serves as a valuable reference standard and research chemical for pharmaceutical R&D, life science research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key bioactive lead compound for investigating new anti-cancer therapies and studying apoptosis mechanisms.
• Life Science Research: Utilized in biochemical and cellular assays to study its effects on various cancer cell lines, including breast, prostate, and liver cancers.
• Reference Standard: Serves as a high-purity analytical standard for quality control and identification in natural product extraction and purification processes.
• Anti-protozoal Agent Development: Investigated for its potential efficacy against parasites such as *Plasmodium falciparum* (malaria) and *Leishmania* species.
• Botanical & Natural Product Studies: Used in research focusing on the bioactivity and chemical ecology of *Ailanthus altissima* and related species.

Basic Information

Product Name	Ailanthone
CAS No.	981-15-7
Molecular Formula	C20H24O7
Molecular Weight	376.40 g/mol
Synonyms	Ailanthone; 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,3-dimethyl-8-(1,1-dimethyl-2-propen-1-yl)-9-hydroxy-2,3,4,9-tetrahydro-; 13,18-Dehydroglaucarubinone; 6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 2,3-dihydro-3,3-dimethyl-8-(1,1-dimethyl-2-propenyl)-9-hydroxy-; Glaucarubinone, 13,18-dehydro-; NSC 176325
EINECS	Contact for details

Quality Control

Our Ailanthone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.