Description

Acetohexamide is a first-generation sulfonylurea compound primarily used as an oral hypoglycemic agent. Its core value lies in its ability to stimulate insulin secretion from pancreatic beta cells, effectively managing blood glucose levels. This makes it a critical active pharmaceutical ingredient (API) for the formulation of anti-diabetic medications. Pharmaceutical manufacturers and research institutions globally require this compound for drug development and production.

Application

• Primary Active Pharmaceutical Ingredient (API) in oral anti-diabetic medications for the management of type 2 diabetes mellitus.
• Reference Standard in analytical laboratories for quality control and method validation of drug products.
• Pharmacological Research for studying the mechanisms of sulfonylurea drugs and insulin secretion pathways.
• Formulation Development for creating generic and novel drug delivery systems (e.g., tablets, capsules).
• Biochemical Studies investigating carbohydrate metabolism and endocrine function.

Basic Information

Product Name	Acetohexamide
CAS No.	968-81-0
Molecular Formula	C15H20N2O4S
Molecular Weight	324.40 g/mol
Synonyms	1-[(p-Acetylphenyl)sulfonyl]-3-cyclohexylurea; 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide; Acetohexamidum; Dimelor; Dymelor; Ordimel; Acetexa; Acetohexamid
EINECS	213-536-1

Quality Control

Our Acetohexamide is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance includes rigorous testing for identity, purity, and impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results against specifications for parameters such as assay, related substances, and residual solvents. We adhere to cGMP principles to ensure consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Ensure the storage area is well-ventilated and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.