Description

2,3-Dioxo-1,2,3,4-Tetrahydroquinoxaline-6-Sulfonyl Chloride is a specialized, high-value sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters because it serves as a key reactive intermediate for introducing the quinoxaline-sulfonamide pharmacophore, enabling the development of novel compounds with targeted biological activity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used to develop new herbicides, fungicides, or insecticides with specific modes of action.
• Material Science: Employed in the creation of advanced polymers or functional materials with specific electronic or binding properties.
• Bioconjugation Chemistry: Acts as a reactive handle for labeling biomolecules (proteins, peptides) due to its sulfonyl chloride group's reactivity with amines.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for the production of bespoke fine chemicals and advanced intermediates for clients.

Basic Information

Product Name	2,3-Dioxo-1,2,3,4-Tetrahydroquinoxaline-6-Sulfonyl Chloride
CAS No.	952-10-3
Molecular Formula	C8H5ClN2O4S
Molecular Weight	260.65 g/mol
Synonyms	6-Quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-2,3-dioxo-; 1,2,3,4-Tetrahydro-2,3-dioxoquinoxaline-6-sulfonyl chloride; Quinoxaline-6-sulfonyl chloride, 1,2,3,4-tetrahydro-2,3-dioxo-; 2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride; 6-(Chlorosulfonyl)-1,2,3,4-tetrahydro-2,3-dioxoquinoxaline; TDQSC; Quinoxalinedione sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dioxo-1,2,3,4-Tetrahydroquinoxaline-6-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.