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n-Propylmagnesium Bromide CAS NO 927-77-5
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CAS No.:927-77-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Propylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its primary value lies in its ability to act as a strong nucleophile and base, facilitating the formation of new carbon-carbon bonds. This makes it an essential building block for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize complex organic molecules.
Application
- Pharmaceutical Intermediate Synthesis: A key reagent for constructing carbon skeletons in active pharmaceutical ingredients (APIs) and drug candidates.
- Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and pesticides by introducing propyl groups into target molecules.
- Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and advanced materials requiring specific alkyl chain extensions.
- Academic & Industrial Research: A fundamental tool in organic chemistry laboratories for method development and exploratory synthesis.
- Polymer Chemistry: Can be utilized as an initiator or modifying agent in the synthesis of specialized polymers.
Basic Information
| Product Name | n-Propylmagnesium Bromide |
| CAS No. | 927-77-5 |
| Molecular Formula | C3H7BrMg |
| Molecular Weight | 147.30 g/mol |
| Synonyms | Propylmagnesium Bromide; Magnesium, bromopropyl-; 1-Propylmagnesium Bromide; Bromo(propyl)magnesium; Propylmagnesium Bromide Solution; Grignard Reagent C3; n-PrMgBr; Bromopropane magnesium |
| EINECS | 213-162-0 |
Quality Control
Our n-Propylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay, and impurity profile. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and highly volatile, this product must be stored under a dry, inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat and ignition sources. Recommended storage temperature is 2-8°C for extended stability. Keep away from moisture, strong acids, and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to light yellow solution |
| Concentration (in THF) | 1.0 M, 2.0 M, or 3.0 M (Custom concentrations available) |
| Assay (Titration) | ≥ 95% |
| Identification (IR) | Conforms to structure |
| Water Content (KF) | < 500 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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