Description

4-[4-(Methylsulfonyl)Piperazin-1-Yl]-4-Oxobutanoic Acid is a high-purity synthetic intermediate characterized by its piperazine and butanoic acid functional groups. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical research and development organizations need this material for synthesizing targeted drug candidates, where consistent quality and reliable supply are paramount for successful preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates.
• Protease Inhibitor Research: Used in the development of inhibitors targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or linker in the creation of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology & Probe Development: Utilized in the design of chemical probes for studying protein function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.
• Academic Research: Employed in university and institutional labs for medicinal chemistry and organic synthesis projects.

Basic Information

Product Name	4-[4-(Methylsulfonyl)Piperazin-1-Yl]-4-Oxobutanoic Acid
CAS No.	899019-04-6
Molecular Formula	C9H16N2O5S
Molecular Weight	264.30 g/mol
Synonyms	4-Oxo-4-[4-(methylsulfonyl)-1-piperazinyl]butanoic Acid; 4-(4-Methanesulfonylpiperazin-1-yl)-4-oxobutanoic Acid; Succinic Acid Monoamide with N-(Methylsulfonyl)piperazine; Butanedioic Acid, Mono[4-(methylsulfonyl)-1-piperazinyl]amide; 899019-04-6; 4-(4-Methylsulfonylpiperazin-1-yl)-4-oxobutanoic Acid
EINECS	Contact for details

Quality Control

Our 4-[4-(Methylsulfonyl)Piperazin-1-Yl]-4-Oxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.