Description

2-Chloro-4-Fluoro-3'-(4-Methylpiperazinomethyl) Benzophenone is a high-purity, functionalized benzophenone derivative that serves as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring a benzophenone core substituted with halogen and piperazine groups, makes it a versatile building block for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral in constructing the core structure of potential APIs, leveraging its halogen and amine functionalities for further derivatization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Custom Synthesis Building Block: Employed by fine chemical manufacturers for the contract synthesis of specialized, low-volume compounds for clinical trials.

Basic Information

Product Name	2-Chloro-4-Fluoro-3'-(4-Methylpiperazinomethyl) Benzophenone
CAS No.	898789-12-3
Molecular Formula	C21H22ClFN2O
Molecular Weight	372.87 g/mol
Synonyms	2-Chloro-4-fluoro-3'-(4-methyl-1-piperazinylmethyl)benzophenone; 2-Chloro-4-fluoro-3'-(N-methylpiperazinomethyl)benzophenone; 2-Chloro-4-fluoro-3'-[(4-methylpiperazin-1-yl)methyl]benzophenone; 898789-12-3; Benzophenone, 2-chloro-4-fluoro-3'-(4-methyl-1-piperazinylmethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3'-(4-Methylpiperazinomethyl) Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.