Description

3-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzophenone core functionalized with a methylpiperazine and a trifluoromethyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for central nervous system (CNS) and oncological applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors due to its specific molecular architecture.
• Kinase Inhibitor Synthesis: Serves as a precursor in the creation of targeted kinase inhibitors for oncology research.
• Chemical Biology & Probe Development: Employed in the design of molecular probes for studying protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, non-commercial APIs.
• Academic & Industrial R&D: Used in exploratory chemistry for discovering new pharmacophores and structure-activity relationships.

Basic Information

Product Name	3-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone
CAS No.	898789-06-5
Molecular Formula	C20H21F3N2O
Molecular Weight	362.39 g/mol
Synonyms	4'-Trifluoromethyl-3-(4-methylpiperazinomethyl)benzophenone; 3-[(4-Methylpiperazin-1-yl)methyl]-4'-(trifluoromethyl)benzophenone; 1-Methyl-4-{[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]carbonyl}piperazine; 898789-06-5; 3-(4-Methyl-1-piperazinylmethyl)-4'-(trifluoromethyl)benzophenone; Benzophenone, 3-[(4-methyl-1-piperazinyl)methyl]-4'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(4-Methylpiperazinomethyl)-4'-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.