Description

2-Carboethoxy-3'-(4-Methylpiperazinomethyl) Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its benzophenone core functionalized with a carboethoxy group and a 4-methylpiperazinomethyl substituent. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients, particularly for compounds targeting specific receptors or enzymes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies and bioactivity studies.

Basic Information

Product Name	2-Carboethoxy-3'-(4-Methylpiperazinomethyl) Benzophenone
CAS No.	898788-48-2
Molecular Formula	C22H26N2O3
Molecular Weight	366.46 g/mol
Synonyms	Ethyl 2-[3-[(4-methylpiperazin-1-yl)methyl]benzoyl]benzoate; 2-(Ethoxycarbonyl)-3'-[(4-methylpiperazin-1-yl)methyl]benzophenone; Benzophenone, 2-(ethoxycarbonyl)-3'-[(4-methyl-1-piperazinyl)methyl]-; 898788-48-2
EINECS	Contact for details

Quality Control

Our 2-Carboethoxy-3'-(4-Methylpiperazinomethyl) Benzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.