Description

4'-(4-Methylpiperazinomethyl)-3-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate with the CAS number 898783-93-2. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for research and development chemists, process scale-up engineers, and manufacturers in the global pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in neurological and oncology research.
• API Synthesis: Serves as a crucial building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its piperazine and trifluoromethyl motifs.
• Process Development: Employed in route scouting and scale-up processes for new chemical entities (NCEs).
• Fine Chemical Production: A specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).
• Biochemical Tool Compound: Potential use in developing biochemical probes for target validation in drug discovery.

Basic Information

Product Name	4'-(4-Methylpiperazinomethyl)-3-Trifluoromethylbenzophenone
CAS No.	898783-93-2
Molecular Formula	C21H23F3N2O
Molecular Weight	376.42 g/mol
Synonyms	3-Trifluoromethyl-4'-(4-methylpiperazinomethyl)benzophenone; 4'-(4-Methyl-1-piperazinylmethyl)-3-(trifluoromethyl)benzophenone; 1-({[4-(3-Trifluoromethylbenzoyl)phenyl]methyl})-4-methylpiperazine; 898783-93-2; 4'-(4-Methylpiperazin-1-ylmethyl)-3-(trifluoromethyl)benzophenone; 3-(Trifluoromethyl)-4'-(4-methylpiperazinomethyl)benzophenone; Benzophenone, 4'-(4-methyl-1-piperazinylmethyl)-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4'-(4-Methylpiperazinomethyl)-3-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.