Description

3'-Chloro-4'-Fluoro-2-Pyrrolidinomethyl Benzophenone is a high-purity, advanced pharmaceutical intermediate with the CAS number 898774-73-7. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of high-value active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for pharmacological and biochemical research projects.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-2-Pyrrolidinomethyl Benzophenone
CAS No.	898774-73-7
Molecular Formula	C18H17ClFNO
Molecular Weight	317.79 g/mol
Synonyms	2-[(3-Chloro-4-fluorophenyl)(phenyl)methyl]-1-pyrrolidine; 1-[Bis(3-chloro-4-fluorophenyl)methyl]pyrrolidine (related structure); 3-Chloro-4-fluoro-2-(pyrrolidin-1-ylmethyl)benzophenone; Pyrrolidinomethyl Benzophenone Derivative; 898774-73-7; (3'-Chloro-4'-fluorophenyl)(phenyl)methanone, 2-(pyrrolidinomethyl)-; Benzophenone, 3'-chloro-4'-fluoro-2-(pyrrolidinomethyl)-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-2-Pyrrolidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.