Description

2-Chloro-4-Fluoro-2'-(4-Methylpiperazinomethyl) Benzophenone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new drug candidates, especially in central nervous system (CNS) and oncology research.
• Precursor for Biologically Active Molecules: Used in the construction of complex molecules with potential receptor-binding or enzyme-inhibiting activity.
• Research & Development (R&D): Essential for medicinal chemistry programs in academic, government, and industrial laboratories for structure-activity relationship (SAR) studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial API batches.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	2-Chloro-4-Fluoro-2'-(4-Methylpiperazinomethyl) Benzophenone
CAS No.	898762-21-5
Molecular Formula	C19H20ClFN2O
Molecular Weight	346.83 g/mol
Synonyms	2-Chloro-4-fluoro-2'-[(4-methyl-1-piperazinyl)methyl]benzophenone; 2'-[(4-Methylpiperazin-1-yl)methyl]-2-chloro-4-fluorobenzophenone; Benzophenone, 2-chloro-4-fluoro-2'-[(4-methyl-1-piperazinyl)methyl]-; 898762-21-5; 2-Chloro-4-fluoro-2'-(4-methylpiperazine-1-carbonyl)benzophenone (common misnomer); 2-Cl-4-F-2'-(N-Methylpiperazinomethyl) Benzophenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-2'-(4-Methylpiperazinomethyl) Benzophenone is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.