Description

4-[(Allyloxy)Carbonyl]Piperazine-2-Carboxylic Acid, N1-Fmoc Protected 97%4-Allyl 1-(9-H-Fluoren-9-Ylmethyl) Hydrogen Piperazine-1,2,4-Tricarboxylate is a sophisticated, high-purity building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, protected intermediates in the development of complex molecules. It is primarily utilized in the pharmaceutical and biotechnology sectors for applications such as peptide synthesis and medicinal chemistry.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected piperazine derivative for introducing modified amino acid structures into peptide chains.
• Medicinal Chemistry & Drug Discovery: Used as a versatile scaffold or intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Combinatorial Chemistry Libraries: Employed to create diverse compound libraries for high-throughput screening (HTS) against biological targets.
• Protease Inhibitor Development: Acts as a core component in the design and synthesis of potential protease inhibitors due to its piperazine carboxylic acid structure.
• Chemical Biology Probes: Utilized in the synthesis of labeled or tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis Services: A valuable starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis.

Basic Information

Item	Detail
Product Name	4-[(Allyloxy)Carbonyl]Piperazine-2-Carboxylic Acid, N1-Fmoc Protected 97%4-Allyl 1-(9-H-Fluoren-9-Ylmethyl) Hydrogen Piperazine-1,2,4-Tricarboxylate
CAS No.	898289-65-1
Molecular Formula	C24H24N2O6
Molecular Weight	436.46 g/mol
Synonyms	Fmoc-Pip(Alloc)-OH; 1-Fmoc-4-Alloc-piperazine-2-carboxylic acid; 4-(Allyloxycarbonyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]piperazine-2-carboxylic acid; 4-Alloc-1-Fmoc-piperazine-2-carboxylic acid; Nα-Fmoc-Nδ-Alloc-L-2,4-diaminobutyric acid (piperazine analog); 898289-65-1; 4-Allyl 1-(9H-fluoren-9-ylmethyl) hydrogen piperazine-1,2,4-tricarboxylate
EINECS	Contact for details

Quality Control

Our 4-[(Allyloxy)Carbonyl]Piperazine-2-Carboxylic Acid, N1-Fmoc Protected is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC and NMR to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Total)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.