Description

(S)-3-Benzyl-1-Methyl-Piperazine is a high-purity, chiral piperazine derivative of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of central nervous system (CNS) drugs, receptor antagonists, and other biologically active molecules.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Serves as a building block for developing novel chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Utilized in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library generation.
• Process Chemistry: Investigated for scale-up in the development of efficient, stereoselective manufacturing routes for APIs.

Basic Information

Item	Details
Product Name	(S)-3-Benzyl-1-Methyl-Piperazine
CAS No.	898044-42-3
Molecular Formula	C₁₂H₁₈N₂
Molecular Weight	190.28 g/mol
Synonyms	(S)-1-Methyl-3-benzylpiperazine; (S)-3-Benzyl-1-methylpiperazine; (S)-1-Methyl-3-(phenylmethyl)piperazine; (S)-N-Methyl-3-benzylpiperazine; (3S)-1-Methyl-3-benzylpiperazine; (S)-(-)-3-Benzyl-1-methylpiperazine; 898044-42-3; SCHEMBL2180557
EINECS	Contact for details

Quality Control

Our (S)-3-Benzyl-1-Methyl-Piperazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.