Description

(4-Chloro-Phenyl)-[4-((3R,4R)-4-Hydroxy-Pyrrolidin-3-Yl)-Piperazin-1-Yl]-Methanone CAS NO 897651-93-3 is a high-purity chiral building block and advanced pharmaceutical intermediate featuring a complex piperazine-pyrrolidine scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of targeted therapeutics. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its defined stereochemistry and functionalized heterocyclic core.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and pharmacological studies.

Basic Information

Product Name	(4-Chloro-Phenyl)-[4-((3R,4R)-4-Hydroxy-Pyrrolidin-3-Yl)-Piperazin-1-Yl]-Methanone
CAS No.	897651-93-3
Molecular Formula	C15H20ClN3O2
Molecular Weight	309.79 g/mol
Synonyms	(4-Chlorophenyl)[4-((3R,4R)-4-hydroxypyrrolidin-3-yl)piperazin-1-yl]methanone; 1-[(4-Chlorobenzoyl)-4-((3R,4R)-4-Hydroxypyrrolidin-3-yl)piperazine; (3R,4R)-3-[4-(4-Chlorobenzoyl)piperazin-1-yl]pyrrolidin-4-ol; 897651-93-3; (4-Chloro-Phenyl)-[4-((3R,4R)-4-Hydroxy-Pyrrolidin-3-Yl)-Piperazin-1-Yl]-Methanone; (R,R)-4-(4-(4-Chlorobenzoyl)piperazin-1-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.