Description

tert-Butyl 4-(4-Chlorobenzoyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. It is essential for pharmaceutical R&D laboratories, process development chemists, and manufacturers engaged in the production of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those containing a piperazine pharmacophore.
• API Synthesis: Used in the research and commercial-scale production of Active Pharmaceutical Ingredients (APIs) for various therapeutic applications.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for efficient and cost-effective manufacturing processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	tert-Butyl 4-(4-Chlorobenzoyl)Piperazine-1-Carboxylate
CAS No.	897445-35-1
Molecular Formula	C16H21ClN2O3
Molecular Weight	324.80 g/mol
Synonyms	1-Boc-4-(4-Chlorobenzoyl)piperazine; 4-(4-Chlorobenzoyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-chlorobenzoyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(4-chlorobenzoyl)piperazine; N-Boc-4-(4-Chlorobenzoyl)piperazine; 897445-35-1; 4-(p-Chlorobenzoyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Chlorobenzoyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.